Observing Brain Synapses in Action
(SACRAMENTO, Calif.) - Lin Tian's fascination with neuroscience stems from a deep curiosity about the complexity and elegance of the human brain. As one of only five scientists in the U.S. and Canada - and the first at UC Davis - to be named a 2014 Rita Allen Foundation Scholar, Tian will be developing optical sensors and applications to acquire fundamental insights about how the nervous system functions in health and disease.
"The functioning brain receives thousands of chemical and electrical signals at the synapse, the area of connection between neurons," Tian said. "Understanding how neurons integrate these multiple inputs to transmit information and to shape and refine the neural circuitry itself is an important area of research that can shed light on an array of neurological disorders, including depression, addiction, autism, schizophrenia and epilepsy."
With a five-year, $500,000 grant from the Rita Allen Foundation, Tian will develop imaging tools to obtain a comprehensive view of both excitatory and inhibitory synapses in action at the cellular, tissue and whole-animal levels. She also will apply these tools to uncover the functional organization of cortical layer1 (L1) interneurons in shaping long-range interactions and their link to behavior, which can't be done with current technology, Tian said.
"Understanding how information is transferred across neural circuitry and systems is the key to innovation in the treatment of neurological disorders," she said.
Tian is an assistant professor of biochemistry and molecular medicine at UC Davis. She holds a bachelor's degree in neuroscience from the University of Science and Technology of China and a doctorate in biochemistry, molecular and cell biology from Northwestern University. She completed her postdoctoral training at Howard Hughes Medical Institute Janelia Farm.
Since 1976, more than one hundred young leaders in biomedical science have been selected as Rita Allen Foundation Scholars. The program embraces innovative research with above-average risk and promise. Scholars have gone on to win the Nobel Prize in Physiology or Medicine, the National Medal of Science, the Wolf Prize in Medicine, and the Breakthrough Prize in Life Sciences.
Pet Care | Real Estate | Restaurants | Tech | View All | * Add/Upgrade Business
Placer County News HeadlinesPlacer Valley Sports Complex: Who's Designing It?Placer Valley Sports Complex, Inc. has reached its first major milestone in the building and development of its brand new, state-of-the-art Regional Sports Complex in Roseville.
25 Year Old Arrested as Arson SuspectThe Placer County Sheriff's Office arrested David Petrashishen, 25 for arson following Sunday's fire in Elverta.
California Statewide Fire Summary (7.30.15)California Fire Updates 2015: Yesterday afternoon and evening fire activity in Northern California significantly increased as temperatures hit the triple digits and the winds became very gusty.
Roseville Crime Report Digest Update (7.30.15)Roseville, CA - Weekly crime report digest update for Roseville, July 30, 2015.
State Moonlights as SlumlordIf a recent study to determine the safety of 29 state-owned buildings tells us anything, it's that the state is a terrible landlord
Community Foundations Fund Senior Nutrition ProgramsAuburn, CA - Thanks to additional funding, Seniors First will soon expand a program established to provide homebound seniors with hot meals and daily social interaction
Hot Pink Fun Run in Roseville to benefit Placer Breast Cancer FoundationRoseville, CA -- The Placer Breast Cancer Foundation is hosting the eighth annual Hot Pink Fun Run event in Roseville.
Air Quality Alert in Placer CountyThe Placer County Public Health Officer and Placer County Air Pollution Control District are issuing a joint air quality advisory to notify the public of the potential for poor air quality
Roseville and Lincoln to Host Senior Softball-USA Western NationalsThe 15th Annual Senior Softball-USA Western Nationals (SSUSA) will take place August 3-9 at Foskett Regional Park in Lincoln and Maidu Regional Park in Roseville
California Statewide Fire Summary (7.28.15)California Fire Updates 2015: While most of California saw a rise in temperatures, firefighters across the State continued to make good progress on the 9 active large wildfires.
Roseville Crime Report Digest Update (7.28.15)Crime report digest update for Roseville, California July 28, 2015.
Summer Institute on Neurodevelopmental Disorders August 7thThe 12th Annual UC Davis Summer Institute on Neurodevelopmental Disorders - one of the nation's premier gatherings of health professionals, educators and families
NEWS: In Case You Missed It